Toshiaki Minami Selected Research

(2S,3R,4R)- 3- carboxymethyl- 4- (phenylthio)pyrrolidine- 2- carboxylic acid

6/2013	The action site of the synthetic kainoid (2S,3R,4R)-3-carboxymethyl-4-(4-methylphenylthio)pyrrolidine-2-carboxylic acid (PSPA-4), an analogue of Japanese mushroom poison acromelic acid, for allodynia (tactile pain).
12/2007	A synthetic kainoid, (2S,3R,4R)-3-carboxymethyl-4-(phenylthio)pyrrolidine-2-carboxylic acid (PSPA-1) serves as a novel anti-allodynic agent for neuropathic pain.

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Toshiaki Minami Research Topics

Disease

31	Pain (Aches) 01/2020 - 01/2002
20	Hyperalgesia 01/2020 - 01/2002
12	Neoplasms (Cancer) 10/2019 - 06/2010
9	Neuralgia (Stump Neuralgia) 06/2020 - 04/2003
9	Hemorrhage 04/2017 - 08/2014
8	Postoperative Pain 12/2018 - 10/2004
7	Nausea 12/2018 - 12/2013
6	Lung Neoplasms (Lung Cancer) 04/2016 - 05/2014
5	Inflammation (Inflammations) 06/2021 - 01/2002
4	Pharyngitis (Sore Throat) 10/2017 - 03/2009
4	Paralysis (Palsy) 09/2017 - 08/2015
4	Heart Arrest (Cardiac Arrest) 01/2017 - 05/2015
4	Vomiting 01/2017 - 12/2013
3	Acute Kidney Injury (Acute Renal Failure) 12/2021 - 04/2020
3	Neurologic Manifestations (Neurological Manifestations) 08/2020 - 08/2014
3	Neoplasm Metastasis (Metastasis) 01/2019 - 07/2017
3	Hypoxia (Hypoxemia) 04/2017 - 08/2014
3	Postoperative Nausea and Vomiting (PONV) 04/2016 - 12/2013
3	Myocardial Ischemia (Ischemic Heart Diseases) 04/2016 - 02/2014
3	Venous Thrombosis (Deep-Vein Thrombosis) 11/2012 - 07/2011
2	Sepsis (Septicemia) 12/2021 - 01/2017
2	Shock 01/2021 - 08/2020
2	Urinary Bladder Neoplasms (Bladder Cancer) 10/2020 - 02/2017
2	Transurethral resection syndrome 08/2020 - 04/2015
2	Cancer Pain 01/2019 - 01/2019
2	Hoarseness 10/2017 - 03/2009
2	Pneumoperitoneum 07/2017 - 08/2015
2	Hypotension (Low Blood Pressure) 04/2017 - 08/2016
2	Peripheral Nerve Injuries 01/2017 - 11/2004
2	Trigeminal Neuralgia (Tic Douloureux) 01/2017 - 08/2014
2	Aspiration Pneumonia 12/2016 - 01/2016
2	Unconsciousness (Loss of Consciousness) 06/2016 - 04/2015
2	Blister (Bulla) 04/2016 - 05/2014
2	Abruptio Placentae (Placental Abruption) 02/2016 - 04/2015
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2016 - 01/2015
2	Thrombosis (Thrombus) 01/2016 - 08/2014
2	Infections 12/2015 - 01/2015

Drug/Important Bio-Agent (IBA)

21	Anesthetics (Anesthetic Agents)IBA 04/2017 - 06/2010
8	Dexmedetomidine FDA Link 04/2016 - 05/2014
8	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2016 - 07/2003
6	NociceptinIBA 01/2018 - 10/2002
6	Analgesics (Analgesic Drugs)IBA 09/2017 - 04/2003
6	N-Methylaspartate (NMDA)IBA 01/2016 - 06/2004
5	acromelic acid AIBA 08/2015 - 06/2004
4	AcidsIBA 01/2020 - 06/2004
4	NeuropeptidesIBA 01/2018 - 02/2006
4	Sevoflurane (Ultane)FDA LinkGeneric 01/2017 - 02/2014
4	Pharmaceutical PreparationsIBA 01/2017 - 07/2003
4	Dihydrotachysterol (AT 10)IBA 01/2015 - 10/2002
4	ProstaglandinsIBA 02/2006 - 07/2003
3	Lipocalin-2IBA 06/2021 - 04/2020
3	Dacarbazine (DIC)FDA LinkGeneric 01/2021 - 01/2016
3	SodiumIBA 08/2020 - 08/2014
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 03/2012
3	nocistatinIBA 01/2018 - 03/2012
3	Messenger RNA (mRNA)IBA 01/2016 - 01/2002
3	CarrageenanIBA 01/2016 - 01/2002
3	SteroidsIBA 11/2013 - 07/2011
3	PoisonsIBA 06/2013 - 06/2004
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2007 - 04/2003
3	N- (4- amino- 2- methylquinolin- 6- yl)- 2- (4- ethylphenoxymethyl)benzamideIBA 02/2006 - 10/2002
3	Prostaglandin E Receptors (Prostaglandin E Receptor)IBA 02/2006 - 07/2003
2	stiripentolIBA 06/2020 - 01/2020
2	Carbamazepine (Tegretol)FDA LinkGeneric 01/2020 - 01/2017
2	Formaldehyde (Formol)FDA Link 01/2020 - 10/2002
2	Glycoproteins (Glycoprotein)IBA 01/2020 - 07/2003
2	Yi-Gan SanIBA 01/2019 - 01/2019
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2019 - 01/2019
2	Opioid Peptides (Opioid Peptide)IBA 01/2018 - 02/2006
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2017 - 03/2011
2	EnzymesIBA 01/2017 - 11/2013
2	Dinoprostone (PGE2)FDA Link 01/2016 - 12/2005
2	SugammadexIBA 01/2016 - 08/2015

Therapy/Procedure

32	General Anesthesia 10/2020 - 03/2009
14	Anesthesia 10/2019 - 03/2009
9	Airway Management 09/2016 - 06/2010
7	Epidural Anesthesia 09/2016 - 08/2014
6	Spinal Anesthesia 10/2019 - 01/2015
6	Artificial Respiration (Mechanical Ventilation) 02/2017 - 08/2015
6	Therapeutics 01/2017 - 03/2011
6	Cesarean Section (Caesarean Section) 01/2017 - 04/2015
5	Cardiopulmonary Bypass (Heart-Lung Bypass) 04/2020 - 07/2009
5	Kampo Medicine (Kampo) 12/2018 - 12/2013
5	One-Lung Ventilation 04/2017 - 05/2014
4	Oral Administration 01/2019 - 04/2003
4	Central Venous Catheters 01/2018 - 05/2015
4	Spinal Injections 10/2012 - 08/2004
3	Transurethral Resection of Bladder 04/2017 - 01/2016
3	Resuscitation 01/2017 - 05/2015
3	Catheters 01/2017 - 07/2014
3	Hip Replacement Arthroplasty (Total Hip Replacement) 08/2016 - 08/2011
3	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 04/2016 - 02/2009
2	Gynecologic Surgical Procedures (Gynecologic Surgery) 09/2017 - 01/2017
2	Prostatectomy (Retropubic Prostatectomy) 07/2017 - 08/2016
2	Analgesia 01/2017 - 04/2005
2	Pain Management 01/2017 - 11/2004
2	Stents 06/2016 - 06/2010
2	Laryngoscopes 04/2016 - 01/2015
2	Spinal Fusion (Spondylosyndesis) 02/2016 - 05/2015
2	Hysterectomy 01/2016 - 12/2015